c-RET Antibody

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NSJ Bioreagents
Product Code: NSJ-F53523
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F53523-0.1ML0.1 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgM k
Antibody Clonality: Monoclonal
Antibody Clone: 188CT11.2.3
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the c-RET antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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c-RET antibody western blot analysis in A549 lysate.
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c-RET antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue.
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Confocal immunofluorescent analysis of c-RET antibody with MDA-MB231 cells followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). Actin filaments have been labeled with Alexa Fluor 555 Phalloidin (red). DAPI was used as a nuclear counterstain (blue).
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Western blot testing of mouse heart lysate with c-RET antibody.
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c-RET antibody western blot analysis in A549 lysate.
c-RET antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue.
Confocal immunofluorescent analysis of c-RET antibody with MDA-MB231 cells followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). Actin filaments have been labeled with Alexa Fluor 555 Phalloidin (red). DAPI was used as a nuclear counterstain (blue).
Western blot testing of mouse heart lysate with c-RET antibody.

Documents

Further Information

Application Details:
Western blot: 1:500-1:16000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
Application Note:
Titration of the c-RET antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Format:
Ascites
Formulation:
In ascites with 0.09% sodium azide
Immunogen:
This c-RET antibody was raised using purified His-tagged recombinant human c-RET.
Limitation:
This c-RET antibody is available for research use only.
Purity:
Ascites
Uniprot #:
P07949