Human Perforin ELISA Kit

Diaclone
Product Code: 850.860.048
Product Group: ELISA Kits
Supplier: Diaclone
CodeSizePrice
850.860.0481 x 48 Discovery (pre-coated)£227.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)

Further Information

Assay Range:
62.5-2000 pg/ml
Cross reaction:
No cross reactivity with Trail TRAIL R3 TRAIL R4 Granzyme B TNFα IFNγ Fas Fas L IL-1b IL-2
Description:
Diaclone ELISA Kits include pre-coated strip plates biotinylated secondary antibody standards controls (where applicable) buffers streptavidin-HRP TMB stop reagents and a detailed procedure.
Detection Target:
Perforin
Incubation:
2h45
Reactivity:
Human
Research Area:
Cytotoxic Molecules
Sample Size:
100 µl
Sample Types:
Supernatant Buffered Solutions Not suitable for use with serum and plasma.
Sensitivity:
40 pg/ml
Specificity:
Recognizes natural human Perforin

References

  1. Aydemir T. B. et al. J. Leukoc. Biol.2009; jlb.1208759.. Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-{gamma} expression in activated human T cells. https://www.ncbi.nlm.nih.gov/pubmed/19401385
  2. Chiossone L. et al. Blood2007; 109: 3767 - 3775. Molecular analysis of the methylprednisolone-mediated inhibition of NK cell function: evidence for different susceptibility of IL-2-versus IL-15-activated NK cells. https://www.ncbi.nlm.nih.gov/pubmed/17234744
  3. Kubler A. et al.Blood2014?; 124(26): 3914-3923. Both mature KIR+ and immature KIR- NK cells control pediatric acute B-cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice. https://www.ncbi.nlm.nih.gov/pubmed/25359989
  4. Lagadari M. et al. Int. Immunol.2009; 21(6): 667-677.. Lysophosphatidic acid inhibits the cytotoxic activity of NK cells: involvement of Gs protein-mediated signaling. https://www.ncbi.nlm.nih.gov/pubmed/19461126
  5. Muller L. et al.Part Fibre Toxicol.2013;10:16. Diesel exhaust particles modify natural killer cell function and cytokine release.. https://www.ncbi.nlm.nih.gov/pubmed/23618096
  6. Oberst M. D. et al. Mabs2016; 6(6):1571-84. CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.. https://www.ncbi.nlm.nih.gov/pubmed/25484061
  7. Schmidt S. et al.The Journal of Infectious Disease 2010: jiq062. Human Natural Killer Cells Exhibit Direct Activity against Aspergillus fumigatus Hyphae But Not Against Resting Conidia. https://www.ncbi.nlm.nih.gov/pubmed/21208932
  8. Stary G. et al. J Exp Med.2007;(204): 1441-1451. Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. https://www.ncbi.nlm.nih.gov/pubmed/17535975