Human Granzyme B ELISA Kit

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Diaclone
Product Code: 850.790.048
Product Group: ELISA Kits
Supplier: Diaclone
CodeSizePrice
850.790.0481 x 48 Discovery (pre-coated)£227.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)

Further Information

Assay Range:
31.25-1000 pg/ml
Cross reaction:
No cross reactivity with Trail TNFα IFNγ Fas IL-1α IL-4 IL-6 IL-8 IL-13
Description:
Diaclone ELISA Kits include pre-coated strip plates biotinylated secondary antibody standards controls (where applicable) buffers streptavidin-HRP TMB stop reagents and a detailed procedure.
Detection Target:
Granzyme B
Incubation:
3h45
Reactivity:
Human
Research Area:
Cytotoxic Molecules
Sample Size:
100 µl
Sample Types:
Serum Plasma Cell culture supernatant
Sensitivity:
20 pg/ml
Specificity:
Recognizes both natural and recombinant human Granzyme B

References

  1. Anguille S. et al.PLoS One2012; 7(12): e51851. Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential.. https://www.ncbi.nlm.nih.gov/pubmed/23284789
  2. Ariizumi H. et al.Intern Med. 2017;56(14):1855-1861.. Post-cytokine-release Salt Wasting as Inverse Tumor Lysis Syndrome in a Non-cerebral Natural Killer-cell Neoplasm.. https://www.ncbi.nlm.nih.gov/pubmed/28717082
  3. Hodge S. et al. Clin Exp Immunol.2009; 158(2): 230-6. Increased levels of T cell granzyme b in bronchiolitis obliterans syndrome are not suppressed adequately by current immunosuppressive regimens. https://www.ncbi.nlm.nih.gov/pubmed/19737140
  4. Karlsson H. et al.PLoS One2015; 10(12): e0144787. Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors.. https://www.ncbi.nlm.nih.gov/pubmed/26700307
  5. Muller L. et al.Part Fibre Toxicol.2013;10:16. Diesel exhaust particles modify natural killer cell function and cytokine release.. https://www.ncbi.nlm.nih.gov/pubmed/23618096
  6. Oberst M. D. et al.Mabs2014; 6(6): 1571-84. CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.. https://www.ncbi.nlm.nih.gov/pubmed/25484061
  7. Rudnicka K. et al.Innate Immunity;2014: 1753425913518225. Helicobacter pylori-driven modulation of NK cell expansion intracellular cytokine expression and cytotoxic activity. https://www.ncbi.nlm.nih.gov/pubmed/24448078
  8. Stary G. et al. J Exp Med.2007;(204): 1441-1451.. Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. https://www.ncbi.nlm.nih.gov/pubmed/17535975
  9. Tack G. J. et al.BMC Gastroenterol.2012;12:159. Serum parameters in the spectrum of coeliac disease: beyond standard antibody testing--a cohort study. https://www.ncbi.nlm.nih.gov/pubmed/23145841
  10. Tanaka T. et al. Int Immunol. 2007; 19(2): 163-73.. Lipophilic statins suppress cytotoxicity by freshly isolated natural killer cells through modulation of granule exocytosis. https://www.ncbi.nlm.nih.gov/pubmed/17182966
  11. Watchmaker P. B. et al. J. Immunol.2008; 180(6): 3857-3865.. Memory CD8+ T Cells Protect Dendritic Cells from CTL Killing. https://www.ncbi.nlm.nih.gov/pubmed/18322193