Mouse Anti-Human CD53 Monoclonal Antibody, Clone TS53, Azide free

Diaclone
Product Code: 857.760.000
Product Group: Primary Antibodies
Supplier: Diaclone
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857.760.000200ug/200ul£287.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: TS53
Regulatory Status: RUO
Target Species: Human

Further Information

Antigen:
CD53
Antigen Synonyms:
MOX44
Conjugate:
Azide free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG8. x Balb/c spleen cells
Immunisation:
Jurkat cell line
Reactivity:
Human
Research Area:
TetraspaninCD Markers
Specificity:
Recognises the MEM-53 antigen a 30-50 kda (smear) protein

References

  1. Charrin S. et al. Biochem. Biophys. Res. Commun. 2003; 304(1): 107-112. Multiple levels of interactions within the tetraspanin web. https://www.ncbi.nlm.nih.gov/pubmed/12705892
  2. Charrin S. et al. Biochem. J. 2003; 373(Pt 2): 409-421. EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells. https://www.ncbi.nlm.nih.gov/pubmed/12708969
  3. Charrin S. et al. Eur. J. Immunol. 2003; 33(9): 2479-2489. A physical and functional link between cholesterol and tetraspanins. https://www.ncbi.nlm.nih.gov/pubmed/12938224
  4. Charrin S. et al. FEBS Lett. 2002; 516(1-3): 139-144. Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation. https://www.ncbi.nlm.nih.gov/pubmed/11959120
  5. Poloso N. J. et al. J Immunol.2006; 177(8): 5451-8.. CDw78 defines MHC class II-peptide complexes that require Ii chain-dependent lysosomal trafficking not localization to a specific tetraspanin membrane microdomain. https://www.ncbi.nlm.nih.gov/pubmed/17015731