Mouse Anti-Human CD253 BioActive Antibody, Clone B-T24, Azide free

Diaclone
Product Code: 853.090.000
Product Group: Primary Antibodies
Supplier: Diaclone
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853.090.000200ug/200ul£232.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-T24
Regulatory Status: RUO
Target Species: Human
Application: Functional Study

Further Information

Activity:
Inhibits TRAIL induced apoptosis
Antigen:
TRAIL / APO2L
Antigen Synonyms:
APO2L TRAIL
Biological Acivity:
Inhibits TRAIL induced apoptosis
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TRAIL
Reactivity:
Human
Research Area:
ApoptosisCD Markers
Specificity:
Recognises the TRAIL APO2L antigen a 32 kDa protein
Workshop:
VIII

References

  1. RyuS. et al.BMC Cancer 2018 Apr 16;18(1):432. The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells.. https://www.ncbi.nlm.nih.gov/pubmed/29661248
  2. Sabour Alaoui S. et al. PLoS One2012; 7(3): e33609. TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus.. https://www.ncbi.nlm.nih.gov/pubmed/22438963
  3. Vermot-Desroches C. et al. Cell Immunol. 2005;236(1-2):86-91. Characterization of monoclonal antibodies directed against trail or trail receptors. https://www.ncbi.nlm.nih.gov/pubmed/16157319