Mouse Anti-Human IL-4 BioActive Antibody, Clone B-S4, Azide free

Diaclone
Product Code: 855.030.000
Product Group: Primary Antibodies
Supplier: Diaclone
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855.030.000200ug/200ul£232.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-S4
Regulatory Status: RUO
Target Species: Human
Application: Functional Study

Further Information

Activity:
Inhibits IL-4 induced proliferation on TF1 cells
Antigen:
IL-4
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human IL-4
Reactivity:
Human
Research Area:
Cytokines / Growth Factors
Specificity:
Recognises both natural and recombinant human IL-4

References

  1. Conticello C. et al. J Immunol.2004; 172(9): 5467-77.. IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins. https://www.ncbi.nlm.nih.gov/pubmed/15100288
  2. Stassi G. et al. Cancer Res.2003; 63(20): 6784-90.. Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10.. https://www.ncbi.nlm.nih.gov/pubmed/14583474
  3. Todaro M. et al. Cancer Res.2006; 66(3): 1491-9.. Autocrine production of interleukin-4 and interleukin-10 is required for survival and growth of thyroid cancer cells. https://www.ncbi.nlm.nih.gov/pubmed/16452205
  4. Venet F. et al. J Immunol.2006; 177(9): 6540-7.. Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism. https://www.ncbi.nlm.nih.gov/pubmed/17056586