Mouse Anti-Human IL-10 BioActive Antibody, Clone B-S10, Azide free

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Diaclone
Product Code: 855.100.000
Product Group: Primary Antibodies
Supplier: Diaclone
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855.100.000200ug/200ul£232.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-S10
Regulatory Status: RUO
Target Species: Human
Application: Functional Study

Further Information

Activity:
Inhibits IL-10 induced proliferation on MC/9 cell line
Antigen:
IL-10
Biological Acivity:
Blocks IL-10 induced inhibition of IL-6 synthesis on LPS activated monocytes
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human IL-10
Reactivity:
Human Mouse
Research Area:
Cytokines / Growth Factors
Specificity:
Recognises both natural and recombinant human IL-10

References

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  2. Brok H. P. et al. J Immunol.2002; 169(11): 6554-63.. Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody..
  3. Debili N.et al. Blood2001; 97(7): 2023-2030.. Different expression of CD41 on human lymphoid and myeloid progenitors from adults and neonates.. https://www.ncbi.nlm.nih.gov/pubmed/11264167
  4. Egeler R. M. et al. Blood1999; 94(12): 4195-201.. Differential In situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment. https://www.ncbi.nlm.nih.gov/pubmed/10590064
  5. Fontana S. et al. Blood2003; 102(12): 4099-106.. Functional defects of dendritic cells in patients with CD40 deficiency. https://www.ncbi.nlm.nih.gov/pubmed/12893749
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  10. Naji A. et al. Blood2007;110(12):3936-48. CD3+CD4low and CD3+CD8low are induced by HLA-G: novel human peripheral blood suppressor T cell subsets involved in transplant acceptance. https://www.ncbi.nlm.nih.gov/pubmed/17804694
  11. Proust R et al. Stem Cell Res Ther. 2020; 11: 172. . Cord blood-endothelial colony forming cells are immunotolerated and participate at post-ischemic angiogenesis in an original dorsal chamber immunocompetent mouse model. https://pubmed.ncbi.nlm.nih.gov/32381102/
  12. Ravirajan C.T. et al. 2004; 43(4) : 442 - 447. Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody. https://www.ncbi.nlm.nih.gov/pubmed/15024133
  13. Schandene L. et al. J Immunol.1994; 152(9): 4368-74.. B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10. https://www.ncbi.nlm.nih.gov/pubmed/7512591
  14. Schrijver I. A. et al. Brain2001; 124(Pt 8): 1544-54.. Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis. https://www.ncbi.nlm.nih.gov/pubmed/11459746
  15. Shinagawa S. et al.Sci Rep. 2017 Nov 3;7(1):14500. T cells upon activation promote endothelin 1 production in monocytes via IFN-γ and TNF-α.. https://www.ncbi.nlm.nih.gov/pubmed/29101349