Mouse Anti-Human CD130 BioActive Antibody, Clone B-K5, Azide free
| Code | Size | Price |
|---|
| 852.070.000 | 200ug/200ul | £232.00 |
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Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-K5
Regulatory Status: RUO
Target Species: Human
Application: Functional Study
Further Information
Activity:
Inhibits CNTF activity. Inhibits OSM binding to gp130
Antigen:
CD130 / gp130
Antigen Synonyms:
gp130
Biological Acivity:
Inhibits CNTF activity. Inhibits OSM binding to gp130
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Natural soluble gp130
Reactivity:
Human
Research Area:
Cytokine / Chemokine ReceptorsCD Markers
Specificity:
Recognises Gp130 common subunit for IL-6 IL-11 OSM LIF CNTF CT-1 receptors a 130-140 kDa protein
Workshop:
VI
References
- Auguste P. et al. J Biol Chem.1997; 272(25): 15760-4.. Signaling of type II oncostatin M receptor. https://www.ncbi.nlm.nih.gov/pubmed/9188471
- Avril P. et al. J Bone Oncol.2016?;5(1): 5-14. Mesenchymal stem cells increase proliferation but do not change quiescent state of osteosarcoma cells: Potential implications according to the tumor resection status. https://www.ncbi.nlm.nih.gov/pubmed/26998421
- Baumann H. et al. Proc Natl Acad Sci.1996;93(16): 8374-8.. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. https://www.ncbi.nlm.nih.gov/pubmed/8710878
- Chevalier S. et al. J Biol Chem.1996; 271(25): 14764-72.. Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. https://www.ncbi.nlm.nih.gov/pubmed/8662918
- Durda P. J. et al. Mol Cancer Res.2003; 1(6): 411-9.. Induction of "antigen silencing" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression. https://www.ncbi.nlm.nih.gov/pubmed/12692260
- Gu Z. J. et al. J Immunol Methods1996; 190(1): 21-7.. Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor interleukin-6 interleukin-11 leukemia inhibitory factor or oncostatin M. https://www.ncbi.nlm.nih.gov/pubmed/8601708