Mouse Anti-Human CD262 BioActive Antibody, Clone B-K29, Azide free
| Code | Size | Price |
|---|
| 854.860.000 | 200ug/200ul | £232.00 |
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Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-K29
Regulatory Status: RUO
Target Species: Human
Application: Functional Study
Further Information
Activity:
Neutralizes TRAIL induced apoptosis of U937 cell line
Antigen:
TRAIL R2 / DR5
Antigen Synonyms:
DR5 TRAIL R2
Biological Acivity:
Neutralizes TRAIL induced apoptosis of U937 cell line
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TRAIL R2/Fc chimera
Reactivity:
Human
Research Area:
ApoptosisCD Markers
Specificity:
Recognises a 42-46 kDa protein
Workshop:
VIII
References
- Chen J.-J. et al. J. Immunol.2008; 180(12): 8030-8039.. Proteasome Inhibitors Enhance TRAIL-Induced Apoptosis through the Intronic Regulation of DR5: Involvement of NF-{kappa}B and Reactive Oxygen Species-Mediated p53 Activation. https://www.ncbi.nlm.nih.gov/pubmed/18523266
- Sato K. et al. J Exp Med.2006; 203(1): 239-50.. TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. https://www.ncbi.nlm.nih.gov/pubmed/16418392
- Vermot-Desroches C. et al. Cell Immunol. 2005;236(1-2):86-91. Characterization of monoclonal antibodies directed against trail or trail receptors. https://www.ncbi.nlm.nih.gov/pubmed/16157319