Mouse Anti-Human IL-6 Monoclonal Antibody, Clone B-F6, Azide free

Diaclone
Product Code: 855.060.000
Product Group: Primary Antibodies
Supplier: Diaclone
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855.060.000200ug/200ul£232.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-F6
Regulatory Status: RUO
Target Species: Human

Further Information

Antigen:
IL-6
Conjugate:
Azide free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human IL-6
Reactivity:
Human Mouse
Research Area:
Cytokines / Growth Factors
Specificity:
Recognises both natural and recombinant human IL-6

References

  1. Kube D. et al. Blood2001; 98(3): 762-70.. STAT3 is constitutively activated in Hodgkin cell lines. https://www.ncbi.nlm.nih.gov/pubmed/11468177
  2. Voorzanger N. et al. Cancer Res.1996; 56(23): 5499-505.. Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors. https://www.ncbi.nlm.nih.gov/pubmed/8968107
  3. Wijdenes J. et al. Eur. J. Immunol.1995; 25 : 3474-3481. Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/8566040
  4. Wijdenes J. et al. Mol Immuno.1991;l 28(11): 1183-92.. Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/1720501
  5. Zunino S. J. et al. Am J Pathol.1996; 149(2): 653-63.. Immunodetection of histone epitopes correlates with early stages of apoptosis in activated human peripheral T lymphocytes. https://www.ncbi.nlm.nih.gov/pubmed/8702003