Mouse Anti-Human CD156/ADAM-10 Monoclonal Antibody, Clone 11G2, Azide free

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Diaclone
Product Code: 857.800.000
Product Group: Primary Antibodies
Supplier: Diaclone
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857.800.000200ug/200ul£287.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 11G2
Regulatory Status: RUO
Target Species: Human

Further Information

Antigen:
ADAM-10
Antigen Synonyms:
CD156c
Conjugate:
Azide free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG8. x Balb/c spleen cells
Immunisation:
Jurkat cell line
Reactivity:
Human
Research Area:
Misc
Specificity:
Recognises the ADAM-10 protein either the 70 kDa form or the 97 kDa precursor form

References

  1. Doberstein K. et al.Carcinogenesis 2011; 10.1093/carcin/bgr195. The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma. https://www.ncbi.nlm.nih.gov/pubmed/21880579
  2. Ebsen H. et al. PLoS One2014; 9(7): e102899. Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10).. https://www.ncbi.nlm.nih.gov/pubmed/25036101
  3. Ebsen H. et al.PLoS One2013; 8(10): e76853. Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells.. https://www.ncbi.nlm.nih.gov/pubmed/24130797
  4. Gutwein P. et al. Am J Pathol. 2009; 174(6): 2061-72. CXCL16 Is Expressed in Podocytes and Acts as a Scavenger Receptor for Oxidized Low-Density Lipoprotein. https://www.ncbi.nlm.nih.gov/pubmed/19435795
  5. Gutwein P. et al. J Cell Mol Med.2009; 13(9B): 3809-25. CXCL16 and oxLDL are induced in the onset of diabetic nephropathy. https://www.ncbi.nlm.nih.gov/pubmed/19426159
  6. Hou L. et al. Int Urol Nephrol. 2018 Sep;50(9):1729-1741. PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.. https://www.ncbi.nlm.nih.gov/pubmed/30117015
  7. Lee S. B. et al.PLoS One20116(8): e22312. PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells.. https://www.ncbi.nlm.nih.gov/pubmed/21876729
  8. Mairpady Shambat S. et al.Dis. Model. Mech.2015; 8(11): 1413-1425. Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology. https://www.ncbi.nlm.nih.gov/pubmed/26398950