Human IL-12p70 ELISA Set

Diaclone
Product Code: 851.550.015
Product Group: ELISA Kits
Supplier: Diaclone
CodeSizePrice
851.550.01515 x 96£494.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO

Further Information

Antigen Synonyms:
IL-12
Assay Range:
6.25 -200 pg/ml
Cross reaction:
No cross reactivity with other human cytokines
Description:
Diaclone ELISA Sets include capture and biotinylated detection antibody one standard per plate Streptavidin-HRP TMB and detailed procedure including buffer composition.
Detection Target:
IL-12
Incubation:
From sample to end 3h45
Reactivity:
Human
Research Area:
Cytokines / Growth Factors
Sample Size:
100 µl
Sample Types:
Serum Plasma Cell culture supernatant
Sensitivity:
2.2 pg/ml
Specificity:
Recognizes both natural and recombinant human IL-12. Specific to p70 heterodimer.

References

  1. De Palma G. et al. J. Leukoc. Biol.2010; 87(5): 765-778. Pivotal Advance: Bifidobacteria and Gram-negative bacteria differentially influence immune responses in the proinflammatory milieu of celiac disease. https://www.ncbi.nlm.nih.gov/pubmed/20007908
  2. Haller D. et al. Clin. Diagn. Lab. Immunol. 2002; 9(3): 649 - 657. Activation of human NK cells by staphylococci and lactobacilli requires cell contact-dependent costimulation by autologous monocytes. https://www.ncbi.nlm.nih.gov/pubmed/11986274
  3. Litjens N.H.R. et al. J. invest. Dermatol. 2004; 122(4) : 923 - 926. Psoriasis is not associated with IL-12p70/IL-12p40 production and IL12B promoter polymorphism. https://www.ncbi.nlm.nih.gov/pubmed/15102082
  4. Puig-Kr?ger A. et al. Blood 2001; 98(7): 2175 - 2182. Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells. https://www.ncbi.nlm.nih.gov/pubmed/11568005
  5. Puig-Kroger A. et al. J Leukoc Biol.2003; 73(4): 482-92.. Peritoneal dialysis solutions inhibit the differentiation and maturation of human monocyte-derived dendritic cells: effect of lactate and glucose-degradation products. https://www.ncbi.nlm.nih.gov/pubmed/12660223
  6. Rask C. et al.Clin Exp Immunol.2013 172(2): 321-32. Differential effect on cell-mediated immunity in human volunteers after intake of different lactobacilli.. https://www.ncbi.nlm.nih.gov/pubmed/23574328
  7. Szpakowski P. et al. J Immunol Res. 2015: 359153. Dendritic Cell Activity Driven by Recombinant Mycobacterium bovis BCG Producing Human IL-18 in Healthy BCG Vaccinated Adults. https://www.ncbi.nlm.nih.gov/pubmed/26339658
  8. Urzainqui A. et al. J. Immunol. 2007;179(11): 7457-7465.. Functional Role of P-Selectin Glycoprotein Ligand 1/P-Selectin Interaction in the Generation of Tolerogenic Dendritic Cells. https://www.ncbi.nlm.nih.gov/pubmed/18025190
  9. von Bergwelt-Baildon M. S. et al. Blood2006; 108(1): 228-37.. CD25 and indoleamine 23-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. https://www.ncbi.nlm.nih.gov/pubmed/16522817
  10. Zhang Q. et al. Infect Immun.2006; 74(8): 4735-43.. Regulation of production of mucosal antibody to pneumococcal protein antigens by T-cell-derived gamma interferon and interleukin-10 in children. https://www.ncbi.nlm.nih.gov/pubmed/16861661

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