Human CD138 ELISA Set
| Code | Size | Price |
|---|
| 851.620.010 | 10 x 96 | £425.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Further Information
Antigen Synonyms:
Syndecan-1
Assay Range:
8-256 ng/ml
Cross reaction:
No cross reactivity with other human soluble molecules
Description:
Diaclone ELISA Sets include capture and biotinylated detection antibody one standard per plate Streptavidin-HRP TMB and detailed procedure including buffer composition.
Detection Target:
CD138 / Syndecan-1
Incubation:
From sample to end 1h45
Reactivity:
Human
Research Area:
Cell Adhesion
Sample Size:
100 µl
Sample Types:
Serum Plasma Cell culture supernatant
Sensitivity:
4.94 ng/ml
Specificity:
Recognizes natural human soluble syndecan-1
References
- Chen L. and R. D. Sanderson PLoS One2009; 4(3): e4947. Heparanase regulates levels of syndecan-1 in the nucleus.. https://www.ncbi.nlm.nih.gov/pubmed/19305494
- Kelly T. et al. Cancer Res. 2003; 63(24): 8749 - 8756. High heparanase activity in multiple myeloma is associated with elevated microvessel density. https://www.ncbi.nlm.nih.gov/pubmed/14695190
- Kelly T. et al. J Bone Miner Res.2010?; 25(6): 1295-304. Tumor-derived syndecan-1 mediates distal cross-talk with bone that enhances osteoclastogenesis.. https://www.ncbi.nlm.nih.gov/pubmed/20200931
- Khotskaya Y. B. et al. J. Biol. Chem.2009; 284(38): 26085-26095.. Syndecan-1 Is Required for Robust Growth Vascularization and Metastasis of Myeloma Tumors in Vivo.. https://www.ncbi.nlm.nih.gov/pubmed/19596856
- Purushothaman A. et al. J. Biol. Chem.2008; M806266200.. Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma.. https://www.ncbi.nlm.nih.gov/pubmed/18812315
- Seidel C. et al. Blood 2000; 96(9): 3139 - 3146. High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity. https://www.ncbi.nlm.nih.gov/pubmed/11049995
- Yang Y. et al. J Biol Chem.2007;282: 13326 - 13333 . Heparanase enhances syndecan-1 shedding: A novel mechanism for stimulation of tumor growth and metastasis. https://www.ncbi.nlm.nih.gov/pubmed/17347152
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