Mouse Anti-Human CD25 Monoclonal Antibody, Clone B-B10, Azide free

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Diaclone
Product Code: 852.000.005
Product Group: Primary Antibodies
Supplier: Diaclone
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852.000.005500ug/500ul£419.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-B10
Regulatory Status: RUO
Target Species: Human

Further Information

Activity:
Inhibits mixed lymphocyte culture
Antigen:
CD25 / IL-2R
Antigen Synonyms:
IL-2R α-Chain
Biological Acivity:
Inhibits mixed lymphocyte culture
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
PHA activated T cells
Reactivity:
Human
Research Area:
Cytokine / Chemokine ReceptorsCD Markers
Specificity:
Recognises the Interleukin 2 Receptor a chain (IL-2 Ra) a 55 kDa protein
Workshop:
IV -V

References

  1. Charlot-Rabiega P. et al. J. Biol. Chem. 2011; 286: 27350 - 27362. Signaling Events Involved in Interleukin 27 (IL-27)-induced Proliferation of Human Naive CD4+ T Cells and B Cells. https://www.ncbi.nlm.nih.gov/pubmed/21669870
  2. Engert A. et al. Int J Cancer1991; 49(3): 450-6.. Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice. https://www.ncbi.nlm.nih.gov/pubmed/1917143
  3. Groux H. et al. J Immunol.1998; 160(7): 3188-93.. Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells. https://www.ncbi.nlm.nih.gov/pubmed/9531274
  4. Herbelin C. et al. Bone Marrow Transplant1994; 13(5): 563-9.. Treatment of steroid-resistant acute graft-versus-host disease with an anti-IL-2-receptor monoclonal antibody (BT 563) in children who received T cell-depleted partially matched related bone marrow transplants. https://www.ncbi.nlm.nih.gov/pubmed/8054909
  5. Herve P. et al. Blood1990; 75(4): 1017-23.. Treatment of corticosteroid resistant acute graft-versus-host disease by in vivo administration of anti-interleukin-2 receptor monoclonal antibody (B-B10). https://www.ncbi.nlm.nih.gov/pubmed/2136244
  6. Herve P. et al. Lancet1988; 2(8619): 1072-3.. Treatment of acute graft-versus-host disease with monoclonal antibody to IL-2 receptor. https://www.ncbi.nlm.nih.gov/pubmed/2903293
  7. Heyll A. et al. Dtsch Med Wochenschr.1991; 116(22): 852-6.. Therapy of multiple myeloma by allogeneic bone marrow transplantation. https://www.ncbi.nlm.nih.gov/pubmed/1903693
  8. Kap Y. S. et al. Journal of Histochemistry & Cytochemistry2009?; 57(12): 1159-1167.. A Monoclonal Antibody Selection for Immunohistochemical Examination of Lymphoid Tissues From Non-human Primates. https://www.ncbi.nlm.nih.gov/pubmed/19729671
  9. Mousson C. et al. Transplant Proc.1995; 27(2): 1727-8.. CD4 and CD25 monoclonal antibody cocktail in kidney transplant rejection prophylaxis: clinical results of a pilot study. https://www.ncbi.nlm.nih.gov/pubmed/7725472
  10. Nakatani T. et al. Protein Eng.1994; 7(3): 435-43.. Humanization of mouse anti-human IL-2 receptor antibody B-B10. https://www.ncbi.nlm.nih.gov/pubmed/8177893
  11. Nevill T. J. et al. Blood1998; 92(6): 1910-7.. Cytogenetic abnormalities in primary myelodysplastic syndrome are highly predictive of outcome after allogeneic bone marrow transplantation. https://www.ncbi.nlm.nih.gov/pubmed/9731047
  12. Oppmann B. et al. Immunity2000; 13(5): 715-25.. Novel p19 protein engages IL-12p40 to form a cytokine IL-23 with biological activities similar as well as distinct from IL-12. https://www.ncbi.nlm.nih.gov/pubmed/11114383
  13. Ozsahin H. et al. Blood1998; 92(8): 2719-24.. Successful treatment of invasive aspergillosis in chronic granulomatous disease by bone marrow transplantation granulocyte colony-stimulating factor-mobilized granulocytes and liposomal amphotericin-B. https://www.ncbi.nlm.nih.gov/pubmed/9763555
  14. Racadot E. et al. Bone Marrow Transplant1995; 15(5): 669-77.. Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients. https://www.ncbi.nlm.nih.gov/pubmed/7670394
  15. Racadot E. et al. Transplant Proc.1995; 27(2): 1672-3.. Outcome of lymphocyte subsets and cytokines during combined CD4/anti-IL-2R monoclonal antibody therapy in kidney transplantation. https://www.ncbi.nlm.nih.gov/pubmed/7536975