Mouse Anti-Human CD130 Monoclonal Antibody, Clone B-K11, Azide free
| Code | Size | Price |
|---|
| 852.100.005 | 500ug/500ul | £419.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: B-K11
Regulatory Status: RUO
Target Species: Human
Further Information
Antigen:
CD130 / gp130
Antigen Synonyms:
gp130
Conjugate:
Azide free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Natural soluble gp130
Reactivity:
Human
Research Area:
Cytokine / Chemokine ReceptorsCD Markers
Specificity:
Recognises the Gp130 common subunit for IL-6 IL-11 OSM LIF CNTF CT-1 receptors a 130-140 kDa protein
Workshop:
VI
References
- Chevalier S. et al. J Biol Chem.1996; 271(25): 14764-72.. Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. https://www.ncbi.nlm.nih.gov/pubmed/8662918
- Guillet C. et al. J Neurosci.1999; 19(4): 1257-62.. Ciliary neurotrophic factor is a regulator of muscular strength in aging. https://www.ncbi.nlm.nih.gov/pubmed/9952403
- M?ller-Newen G. et al. J. Biol. Chem. 2000; 275 (7) : 4578 - 4586. Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/10671483
- Muller-Newen G. et al. Eur J Biochem1996; 236(3): 837-42.. Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing. https://www.ncbi.nlm.nih.gov/pubmed/8665902