Mouse Anti-Human CD2 Monoclonal Antibody, Clone B-E2, Azide free

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Diaclone
Product Code: 852.500.005
Product Group: Primary Antibodies
Supplier: Diaclone
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852.500.005500ug/500ul£419.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: B-E2
Regulatory Status: RUO
Target Species: Human

Further Information

Activity:
Inhibits mixed lymphocyte culture
Antigen:
CD2 / LFA-2
Antigen Synonyms:
LFA-2
Biological Acivity:
Inhibits mixed lymphocyte culture
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Human thymocytes
Reactivity:
Human
Research Area:
T CellsCD Markers
Specificity:
Recognises the Lymphocyte Function associated Antigen-2 (LFA-2) a 50 kDa protein
Workshop:
V

References

  1. Cavazzana-Calvo M. et al. Br J Haematol.1996; 93(1): 131-8.. A phase II trial of partially incompatible bone marrow transplantation for high-risk acute lymphoblastic leukaemia in children: prevention of graft rejection with anti-LFA-1 and anti-CD2 antibodies. Societe Francaise de Greffe de Moelle Osseuse. https://www.ncbi.nlm.nih.gov/pubmed/8611446
  2. Dupuis-Girod S. et al. Pediatrics2006; 118(1): e205-11.. Successful allogeneic hemopoietic stem cell transplantation in a child who had anhidrotic ectodermal dysplasia with immunodeficiency. https://www.ncbi.nlm.nih.gov/pubmed/16769798
  3. Jabado N. et al. Blood1997; 90(12): 4743-8.. Treatment of familial hemophagocytic lymphohistiocytosis with bone marrow transplantation from HLA genetically nonidentical donors. https://www.ncbi.nlm.nih.gov/pubmed/9389690
  4. Jabado N. et al. Pediatrics1996; 98(3 Pt 1): 420-8.. Bone marrow transplantation from genetically HLA-nonidentical donors in children with fatal inherited disorders excluding severe combined immunodeficiencies: use of two monoclonal antibodies to prevent graft rejection. https://www.ncbi.nlm.nih.gov/pubmed/8784367
  5. Kap Y. S. et al. Journal of Histochemistry & Cytochemistry2009?; 57(12): 1159-1167.. A Monoclonal Antibody Selection for Immunohistochemical Examination of Lymphoid Tissues From Non-human Primates. https://www.ncbi.nlm.nih.gov/pubmed/19729671
  6. Przepiorka D. et al. Blood1998; 92(11): 4066-71.. A phase II study of BTI-322 a monoclonal anti-CD2 antibody for treatment of steroid-resistant acute graft-versus-host disease. https://www.ncbi.nlm.nih.gov/pubmed/9834211
  7. Racadot E. et al. Bone Marrow Transplant1995; 15(5): 669-77.. Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients. https://www.ncbi.nlm.nih.gov/pubmed/7670394
  8. Tiberghien P. et al. Blood 2001; 97(1) : 63 -72. Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft. https://www.ncbi.nlm.nih.gov/pubmed/11133743