Mouse Anti-Human CD264 Monoclonal Antibody, Clone B-P30, Azide free
| Code | Size | Price |
|---|
| 853.130.005 | 500ug/500ul | £419.00 |
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Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-P30
Regulatory Status: RUO
Target Species: Human
Further Information
Antigen:
TRAIL R4 / DcR2
Antigen Synonyms:
DcR2 TRAIL R4
Conjugate:
Azide free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TRAIL R4/Fc chimera
Reactivity:
Human
Research Area:
ApoptosisCD Markers
Specificity:
Recognises TRAIL R4 (DcR2) a 44.2 kDa protein
References
- Jacquemin G. et al. Haematologica 2012; 97: 38 - 46. Quercetin-mediated Mcl-1 and surviving downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells. https://www.ncbi.nlm.nih.gov/pubmed/21933852
- Lalaoui N. et al.PLoS One2011; 6(5): e19679. TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT.. https://www.ncbi.nlm.nih.gov/pubmed/21625476
- Merino D. et al. Mol Cell Biol.2005; 26(19): 7046-55.. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.. https://www.ncbi.nlm.nih.gov/pubmed/16980609
- Morizot A. et al. Cell Death Differ.2011; 18(4): 700-11. Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level.. https://www.ncbi.nlm.nih.gov/pubmed/21072058
- Morle A. et al.Cell Death Dis.2015?; 6: e1633. Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion. . https://www.ncbi.nlm.nih.gov/pubmed/25675293