Mouse Anti-Human CD3 Monoclonal Antibody, Clone B-B11, Azide free

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Diaclone
Product Code: 854.010.005
Product Group: Primary Antibodies
Supplier: Diaclone
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854.010.005500ug/500ul£419.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-B11
Regulatory Status: RUO
Target Species: Human

Further Information

Activity:
Induces T lymphocyte stimulation and proliferation
Antigen:
CD3
Biological Acivity:
Induces T lymphocyte stimulation and proliferation
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
PHA activated T cells
Reactivity:
Human
Research Area:
T CellsCD Markers
Specificity:
Recognises a 20-32 kDa protein

References

  1. Dantal J. et al. Transplantation1996; 62(10): 1502-6.. Anti-CD4 MoAb therapy in kidney transplantation--a pilot study in early prophylaxis of rejection. https://www.ncbi.nlm.nih.gov/pubmed/8958279
  2. Galgano D et al. Front Immunol. 2020; 11: 1154. . Alternative UNC13D Promoter Encodes a Functional Munc13-4 Isoform Predominantly Expressed in Lymphocytes and Platelets. https://pubmed.ncbi.nlm.nih.gov/32582217/
  3. Iwamoto S. et al. J. Immunol.2007; 179(3): 1449-1457.. TNF-{alpha} Drives Human CD14+ Monocytes to Differentiate into CD70+ Dendritic Cells Evoking Th1 and Th17 Responses. https://www.ncbi.nlm.nih.gov/pubmed/17641010
  4. Lu X. et al. J. Virol. 2004; 78(13) : 7079 - 7088. Antisense-Mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-Based Vector Results in Severely Attenuated Mutants Incapable of Developing Resistance. https://www.ncbi.nlm.nih.gov/pubmed/15194784
  5. Quintana A. et al.Embo J.2011; 30(19): 3895-912. Calcium microdomains at the immunological synapse: how ORAI channels mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.. https://www.ncbi.nlm.nih.gov/pubmed/21847095
  6. Vermot-Desroches C. et al. Cell Immunol. 2005;236(1-2):86-91. Characterization of monoclonal antibodies directed against trail or trail receptors. https://www.ncbi.nlm.nih.gov/pubmed/16157319
  7. Yent?r SP et al. PLoS One. 2021; 16(1): e0245077 . Immune alterations in subacute sclerosing panencephalitis reflect an incompetent response to eliminate the measles virus. https://pubmed.ncbi.nlm.nih.gov/33411786/
  8. Yu J. et al. Int J Biol Sci.2009; 5(2): 135-46. Antitumor activity of T cells generated from lymph nodes draining the SEA-expressing murine B16 melanoma and secondarily activated with dendritic cells.. https://www.ncbi.nlm.nih.gov/pubmed/19173035
  9. ZhouX. et al.J Physiol. 2018 Jul 15; 596(14): 2681?2698. A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity. https://www.ncbi.nlm.nih.gov/pubmed/29368348
  10. Jung P. et al. eLife. 2021; 10: e66643. . T cell stiffness is enhanced upon formation of immunological synapse. https://pubmed.ncbi.nlm.nih.gov/34313220/