Mouse Anti-Human CD10 Monoclonal Antibody, Clone B-E3, Azide free
| Code | Size | Price |
|---|
| 854.090.005 | 500ug/500ul | £419.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: B-E3
Regulatory Status: RUO
Target Species: Human
Further Information
Activity:
Cytotoxic In association with rabbit complement on CD10+ cells
Antigen:
CD10
Antigen Synonyms:
CALLA
Biological Acivity:
Cytotoxic In association with rabbit complement on CD10+ cells
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Daudi and Raji cell lines
Reactivity:
Human
Research Area:
B Cell AntigensCD Markers
Specificity:
Recognises the Common Acute Lymphoblastic Leukemia Antigen (CALLA) a 100 kDa protein
References
- Geijtenbeek T. B. et al. Blood1999; 94(2): 754-64.. High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia. https://www.ncbi.nlm.nih.gov/pubmed/10397743
- van den Berg T. K. et al. J Immunol;1996; 157(7): 3130-8.. Regulation of sialoadhesin expression on rat macrophages. Induction by glucocorticoids and enhancement by IFN-beta IFN-gamma IL-4 and lipopolysaccharide. https://www.ncbi.nlm.nih.gov/pubmed/8816424
- Pan C. et al. Cancer Res.2003; 63(17): 5526-31.. CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors. https://www.ncbi.nlm.nih.gov/pubmed/14500390