Mouse Anti-Human CD262 Monoclonal Antibody, Clone B-D37, Azide free

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Diaclone
Product Code: 854.870.005
Product Group: Primary Antibodies
Supplier: Diaclone
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854.870.005500ug/500ul£419.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: B-D37
Regulatory Status: RUO
Target Species: Human

Further Information

Activity:
Agonist: induced apoptosis on Jurkat cells. Enhances TRAIL induced apoptosis of U937 cell line
Antigen:
TRAIL R2 / DR5
Antigen Synonyms:
DR5 TRAIL R2
Biological Acivity:
Agonist: induced apoptosis on Jurkat cells. Enhances TRAIL induced apoptosis of U937 cell line
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TRAIL R2/Fc chimera
Reactivity:
Human
Research Area:
ApoptosisCD Markers
Specificity:
Recognises a 42-46 kDa protein
Workshop:
VIII

References

  1. Dufour F. et al. Cell Death Differ.2017; 24(3): 500-510. N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death. https://www.ncbi.nlm.nih.gov/pubmed/28186505
  2. Dufour F. et al.Oncotarget 2017 Feb 7;8(6):9974-9985. TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.. https://www.ncbi.nlm.nih.gov/pubmed/28039489
  3. Iessi E. et al.PLoS One2015; 10(5): e0126526. Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells. https://www.ncbi.nlm.nih.gov/pubmed/26010871
  4. Merino D. et al. Mol Cell Biol.2005; 26(19): 7046-55.. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.. https://www.ncbi.nlm.nih.gov/pubmed/16980609
  5. Vermot-Desroches C. et al. Cell Immunol. 2005;236(1-2):86-91. Characterization of monoclonal antibodies directed against trail or trail receptors. https://www.ncbi.nlm.nih.gov/pubmed/16157319