Mouse Anti-Human IL-12 p40 Monoclonal Antibody, Clone B-P24, Azide free
| Code | Size | Price |
|---|
| 855.130.005 | 500ug/500ul | £419.00 |
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Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: B-P24
Regulatory Status: RUO
Target Species: Human
Further Information
Activity:
Inhibits IL-12 induced proliferation on PHA and IL-2 activated lymphocytes
Antigen:
IL-12p40+p70
Antigen Synonyms:
IL-12/IL23p40 IL-12p70
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human IL-12
Reactivity:
Human
Research Area:
Cytokines / Growth FactorsInnate Immunity
Specificity:
Recognises both natural and recombinant p40 subunit alone and in its IL-12 form (associated with p35) and in its IL-23 form(associated with p19)
References
- Nagai T. et al. J Immunol.2003; 171(10): 5233-43.. Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation. https://www.ncbi.nlm.nih.gov/pubmed/14607924