Mouse Anti-Human IL-6 Monoclonal Antibody, Clone B-E4, Azide free

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Diaclone
Product Code: 857.730.005
Product Group: Primary Antibodies
Supplier: Diaclone
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857.730.005500ug/500ul£419.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: B-E4
Regulatory Status: RUO
Target Species: Human

Further Information

Antigen:
IL-6
Conjugate:
Azide Free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human IL-6
Reactivity:
Human
Research Area:
Cytokines / Growth Factors
Specificity:
Recognises both natural and recombinant human IL-6

References

  1. Kalai M. et al. Blood1997; 89(4): 1319-33.. Analysis of the Human Interleukin-6/Human Interleukin-6 Receptor BindingInterface at the Amino Acid Level: Proposed Mechanism of Interaction. https://www.ncbi.nlm.nih.gov/pubmed/9028955
  2. Lu Z. Y. et al. Blood1995; 86(8): 3123-31.. Measurement of whole body interleukin-6 (IL-6) production: prediction of the efficacy of anti-IL-6 treatments. https://www.ncbi.nlm.nih.gov/pubmed/7579407
  3. Wijdenes J. et al. Mol Immunol.1991; 28(11): 1183-92.. Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/1720501
  4. LeBouder E. et al. J Immunol.2003; 171(12): 6680-9.. Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk.. https://www.ncbi.nlm.nih.gov/pubmed/14662871