Mouse Anti-Human CD81 Monoclonal Antibody, Clone TS81, Azide free

Contact us
Diaclone
Product Code: 857.780.005
Product Group: Primary Antibodies
Supplier: Diaclone
CodeSizePrice
857.780.005500ug/500ul£538.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: TS81
Regulatory Status: RUO
Target Species: Human

Further Information

Antigen:
CD81
Conjugate:
Azide free
Format:
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Hybridoma:
Myeloma X63/AG8. x Balb/c spleen cells
Immunisation:
Jurkat cell line
Reactivity:
Human
Research Area:
TetraspaninB Cell Antigens
Specificity:
Recognises the TAPA-1 antigen a 23 kDa (smear) protein

References

  1. Abache T. et al. J Cell Biochem2007; 102(3): 650-64. The transferrin receptor and the tetraspanin web molecules CD9 CD81 and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells. https://www.ncbi.nlm.nih.gov/pubmed/17407154
  2. Charrin S. et al. Biochem. Biophys. Res. Commun. 2003; 304(1): 107-112. Multiple levels of interactions within the tetraspanin web. https://www.ncbi.nlm.nih.gov/pubmed/12705892
  3. Charrin S. et al. Biochem. J. 2003; 373(Pt 2): 409-421. EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells. https://www.ncbi.nlm.nih.gov/pubmed/12708969
  4. Charrin S. et al. Eur. J. Immunol. 2003; 33(9): 2479-2489. A physical and functional link between cholesterol and tetraspanins. https://www.ncbi.nlm.nih.gov/pubmed/12938224
  5. Charrin S. et al. FEBS Lett. 2002; 516(1-3): 139-144. Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation. https://www.ncbi.nlm.nih.gov/pubmed/11959120
  6. Charrin S. et al. J. Biol. Chem. 2001; 276(17): 14329-14337. The major CD9 and CD81 molecular partner. Identification and characterization of the complexes. https://www.ncbi.nlm.nih.gov/pubmed/11278880
  7. Serman A. et al. Nucleic Acids Res.2007;35(14): 4715-4727.. GW body disassembly triggered by siRNAs independently of their silencing activity. https://www.ncbi.nlm.nih.gov/pubmed/17604308
  8. Silvie O. et al. J Cell Sci.2006; 119(Pt 10): 1992-2002.. Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites. https://www.ncbi.nlm.nih.gov/pubmed/16687736
  9. Verweij F. J. et al.Embo J.2011;30(11): 2115-29. LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-kappaB activation.. https://www.ncbi.nlm.nih.gov/pubmed/21527913
  10. Yalaoui S. et al. PLoS Pathog.2008?; 4(2): e1000010. Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain. https://www.ncbi.nlm.nih.gov/pubmed/18389082
  11. Mathieu M. et al. Nat Commun. 2021; 12: 4389. . Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9. https://pubmed.ncbi.nlm.nih.gov/34282141/