Human IL-12p70 ELISA Kit

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Diaclone
Product Code: 950.070.192
Product Group: ELISA Kits
Supplier: Diaclone
CodeSizePrice
950.070.1922 x 96 (pre-coated)£422.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)

Further Information

Antigen Synonyms:
IL-12
Assay Range:
6.25 -200 pg/ml
Cross reaction:
No cross reactivity with other human cytokines
Description:
Diaclone ELISA Kits include pre-coated strip plates biotinylated secondary antibody standards controls (where applicable) buffers streptavidin-HRP TMB stop reagents and a detailed procedure.
Detection Target:
IL-12
Incubation:
3h45
Reactivity:
Human
Research Area:
Cytokines / Growth Factors
Sample Size:
100 µl
Sample Types:
Serum Plasma Cell culture supernatant
Sensitivity:
2.2 pg/ml
Specificity:
Recognizes both natural and recombinant human IL-12. Specific to p70 heterodimer.

References

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  2. Bellanger A.-P. et al.Clin. Vaccine Immunol. 2013 ; 20(8): 1133-1142.. Human Monocyte-Derived Dendritic Cells Exposed to Microorganisms Involved in Hypersensitivity Pneumonitis Induce a Th1-Polarized Immune Response. https://www.ncbi.nlm.nih.gov/pubmed/23720369
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  9. Gironella J. et al. Gut 2005; 54(9): 1244 - 1253. Anti-inflammatory effects of pancreatitis associated protein in inflammatory bowel disease. https://www.ncbi.nlm.nih.gov/pubmed/15870231
  10. Gosset P. et al. J. Immunol. 2003 ; 170(10):4943 - 4952. Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. https://www.ncbi.nlm.nih.gov/pubmed/12734337
  11. Guo Z. et al. Biomed Rep.2016;5(5): 567-573. Adenovirus co-expressing CD40 ligand and interleukin (IL)-2 contributes to maturation of dendritic cells and production of IL-12. https://www.ncbi.nlm.nih.gov/pubmed/27882218
  12. Hatzfeld-Charbonnier A. S. et al. J Leukoc Biol.2007;81: 1179 - 1187. Influence of heat stress on human monocyte-derived dendritic cell functions with immunotherapeutic potential for antitumor vaccines. https://www.ncbi.nlm.nih.gov/pubmed/17311933
  13. Hernandez C. et al. PLoS One2014?; 9(6): e98458. Progastrin represses the alternative activation of human macrophages and modulates their influence on colon cancer epithelial cells." . https://www.ncbi.nlm.nih.gov/pubmed/24901518
  14. Hessle C. et al. Infect Immun.2000;68(6): 3581-6.. Gram-positive bacteria are potent inducers of monocytic interleukin-12 (IL-12) while gram-negative bacteria preferentially stimulate IL-10 production.. https://www.ncbi.nlm.nih.gov/pubmed/10816515
  15. Hessle C. et al.Clin Exp Immunol.1999; 116(2): 276-82. Lactobacilli from human gastrointestinal mucosa are strong stimulators of IL-12 production.. https://www.ncbi.nlm.nih.gov/pubmed/10337019