Human IL-12p40 + p70 ELISA Kit

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Diaclone
Product Code: 950.075.096
Product Group: ELISA Kits
Supplier: Diaclone
CodeSizePrice
950.075.0961 x 96 (pre-coated)£327.00
Quantity:
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Overview

Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)

Further Information

Antigen Synonyms:
IL-12/IL23p40
Assay Range:
62.5-2000 pg/ml
Cross reaction:
No cross reactivity with other human cytokines. Cross reacts with feline and canine IL-12 p40.
Description:
Diaclone ELISA Kits include pre-coated strip plates biotinylated secondary antibody standards controls (where applicable) buffers streptavidin-HRP TMB stop reagents and a detailed procedure.
Detection Target:
IL-12
Incubation:
1h45
Reactivity:
Human
Research Area:
Cytokines / Growth Factors
Sample Size:
100 µl
Sample Types:
Serum Plasma Cell culture supernatant
Sensitivity:
20 pg/ml
Specificity:
Recognizes the p40 monomer dimer or heterodimer (p40 + p35) forms of the molecule

References

  1. Beyth S. et al. Blood 2005; 105(5): 2214 - 2219. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. https://www.ncbi.nlm.nih.gov/pubmed/15514012
  2. Bogels M. et al. Oncoimmunology2012; 1(6): 798-809.. Carcinoma origin dictates differential skewing of monocyte function.. https://www.ncbi.nlm.nih.gov/pubmed/23162747
  3. Braitch M. et al. Arch Neurol.2008; 65(5): 633-635.. Increased Osteopontin Levels in the Cerebrospinal Fluid of Patients With Multiple Sclerosis.. https://www.ncbi.nlm.nih.gov/pubmed/18474739
  4. Guerra-Laso J. M. et al.Immunology 2015;144(2): 291-301. Microarray analysis of Mycobacterium tuberculosis-infected monocytes reveals IL26 as a new candidate gene for tuberculosis susceptibility.. https://www.ncbi.nlm.nih.gov/pubmed/25157980
  5. Hoonakker M. E. et al. PLoS One2016; 11(8): e0161428.. Vaccine-Mediated Activation of Human TLR4 Is Affected by Modulation of Culture Conditions during Whole-Cell Pertussis Vaccine Preparation. https://www.ncbi.nlm.nih.gov/pubmed/27548265
  6. Nagao Y. et al. Malar J.2008; 7: 113.. Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection. https://www.ncbi.nlm.nih.gov/pubmed/18582375
  7. Rodriguez-Zapata M. et al. Infect. Immun.2010; 78:3272-3279. Human brucellosis is characterized by an intense Th1 profile associated to a defective monocyte function. https://www.ncbi.nlm.nih.gov/pubmed/20404074
  8. Sun Z. et al. J Biomed Res.2012;26(6): 456-66. Serum IL-10 from systemic lupus erythematosus patients suppresses the differentiation and function of monocyte-derived dendritic cells.. https://www.ncbi.nlm.nih.gov/pubmed/23554785
  9. Tenca C. et al. J. Immunol. 2005; 174(11): 6757 - 6763. CD85j (Leukocyte Ig-Like Receptor-1/Ig-Like Transcript 2) Inhibits Human Osteoclast-Associated Receptor-Mediated Activation of Human Dendritic Cells. https://www.ncbi.nlm.nih.gov/pubmed/15905516
  10. Vilisaar J. et al. J Neuroimmune Pharmacol.2015;10(3): 457-67. Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines IFNgamma/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis.. https://www.ncbi.nlm.nih.gov/pubmed/25690155