7-(Diethylamino)-4-(hydroxymethyl)coumarin
| Code | Size | Price |
|---|
| CDX-D1014-M250 | 250 mg | £219.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short term: +20°C, Long term: +20°C
Documents
Further Information
Alternate Names/Synonyms:
7-(diethylamino)-4-(hydroxymethyl)-2H-chromen-2-one; DEACM; DEACM-OH
Appearance:
White to light brown powder.
CAS:
54711-38-5
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302-H315-H319-H335
InChi:
InChi=
1S/C14H17NO3/c1-3-15(4-2)11-5-6-12-10(9-16)7-14(17)18-13(12)8-11/h5-8,16H,3-4,9H2,1-2H3
InChiKey:
NMZSXNOCNJMJQT-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 54711-38-5. Formula: C14H17NO3. MW: 247.29. 7-(Diethylamino)-4-(hydroxymethyl)coumarin (DEACM) is a photolabile compound that emits fluorescence upon irradiation and is used in analytical chemistry as a fluorescent probe. The photocleavable nature of DEACM facilitates its use as a photolabile protecting group for "Caged" bioactive molecules. The "caging" of bioactive molecule with photolabile protecting groups in particular has proven to be a useful tool in biochemical research. Caged compounds in which bioactive substances are inactivated with photolabile protecting groups and can be activated by UV or visible light photoirradiation. DEACM has been successfully applied for caging a wide variety of functional groups. It also has been used as a near infrared (NIR) light responsive chromophore.
MDL:
MFCD03424352
Molecular Formula:
C14H17NO3
Molecular Weight:
247.29
Package Type:
Vial
Precautions:
P261-P305+P351+P338
Product Description:
7-(Diethylamino)-4-(hydroxymethyl)coumarin (DEACM) is a photolabile compound that emits fluorescence upon irradiation and is used in analytical chemistry as a fluorescent probe. The photocleavable nature of DEACM facilitates its use as a photolabile protecting group for "Caged" bioactive molecules. The "caging" of bioactive molecule with photolabile protecting groups in particular has proven to be a useful tool in biochemical research. Caged compounds in which bioactive substances are inactivated with photolabile protecting groups and can be activated by UV or visible light photoirradiation. DEACM has been successfully applied for caging a wide variety of functional groups. It also has been used as a near infrared (NIR) light responsive chromophore.
Purity:
>98% (GC)
Signal Word:
Warning
SMILES:
CCN(CC)C1=CC2=C(C=C1)C(=CC(=O)O2)CO
Solubility Chemicals:
Soluble in chloroform.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.
References
(1) A.V. Pinheiro, et al.; Nucl. Acids Res. 36, e90 (2008) | (2) B.N. Goguen, et al.; JACS 133, 11038 (2011) | (3) Y. Liang, et al.; Biomaterials 100, 76 (2016) | (4) J. Font, et al.; eLife 6, e23545 (2017) | (5) J. Ma, et al.; Molecules 25, 5325 (2020) | (6) H.-M. Hung, et al.; ACS Chem. Biol. 17, 11 (2022)