Naphthol AS phosphate

Chemodex
Product Code: CDX-N0130
Supplier: Chemodex
CodeSizePrice
CDX-N0130-M500500 mg£115.00
Quantity:
CDX-N0130-G0011 g£184.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short term: +4°C, Long term: -20°C

Images

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Chemical Structure

Chemical Structure

Documents

Further Information

Alternate Names/Synonyms:
3-Hydroxy-2-naphthanilide phosphate; HNPP
Appearance:
White to off-white powder.
CAS:
13989-98-5
EClass:
32160000
Form (Short):
solid
Handling Advice:
Keep under inert gas.Very hygroscopic.
InChi:
InChI=1S/C17H14NO5P/c19-17(18-14-8-2-1-3-9-14)15-10-12-6-4-5-7-13(12)11-16(15)23-24(20,21)22/h1-11H,(H,18,19)(H2,20,21,22)
InChiKey:
KVIYXIWBXOQZDN-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 13989-98-5. Formula: C17H14NO5P. MW: BD9837. Naphthol AS phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS phosphate is converted to naphthol AS displaying excitation/emission spectra of 388/516nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting, dot blot applications and in situ PCR.
MDL:
MFCD00036182
Molecular Formula:
C17H14NO5P
Molecular Weight:
343.27
Package Type:
Vial
Product Description:
Naphthol AS phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS phosphate is converted to naphthol AS displaying excitation/emission spectra of 388/516nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting, dot blot applications and in situ PCR.
Purity:
>99% (HPLC)
SMILES:
O=C(NC1=CC=CC=C1)C2=CC3=CC=CC=C3C=C2OP(O)(O)=O
Solubility Chemicals:
Soluble in ethanol (50mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) Z. Lojda, etal.; Histochemie 11, 13 (1967) | (2) A. Vaughan, et al.; Anal. Chem. 43, 721 (1971) | (3) S. West, et al.; Anal. Biochem. 190, 254 (1990) | (4) H.J. Hoeltke, et al.; Anal. Biochem. 207, 24 (1992) | (5) K. Tani, et al.; Appl. Environ. Microbiol. 64, 1536 (1998)