N-Nitrosomorpholine (NMOR)
| Code | Size | Price |
|---|
| CDX-N0370-G001 | 1 g | £242.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short term: +4°C, Long term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
NMOR; Nitrosomorpholine; NSC-139; BRN 0112139
Appearance:
Yellow clear liquid.
CAS:
59-89-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06, GHS08
Handling Advice:
Protect from light and moisture.
Hazards:
H301 - H351
InChi:
InChi=1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2
InChiKey:
ZKXDGKXYMTYWTB-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 59-89-2. Formula: C4H8N2O2. MW: 116.12. N-Nitrosomorpholine (NMOR) is a nitrosamine and is known to be a potent carcinogen associated with cancer development in animals and humans. NMOR can damage DNA and cause mutations in genes that control cell growth and division. It reacts with DNA in vitro to form genotoxic activity, which may lead to cell death or mutagenesis. NMOR is formed in various industrial processes, including the synthesis of certain chemicals and in the preservation of cosmetic and personal care products. This compound can be used as analytical reference material. NMOR is used as a tumor initiator. It is a reagent for preparing carcinogenic animal diseases model. NMOR has other widespread utilization in laboratory and industrial environments. NMOR exhibits potent oxidizing properties, making it valuable in various applications, including as a bulding block for synthesis, environmental monitoring, and as a reagent in laboratory settings. It serves as a vital component in the synthesis of diverse compounds and functions as an analytical reagent.
MDL:
MFCD00039710
Molecular Formula:
C4H8N2O2
Molecular Weight:
116.12
Package Type:
Vial
PG:
III
Precautions:
P201 - P301 + P310 + P330
Product Description:
N-Nitrosomorpholine (NMOR) is a nitrosamine and is known to be a potent carcinogen associated with cancer development in animals and humans. NMOR can damage DNA and cause mutations in genes that control cell growth and division. It reacts with DNA in vitro to form genotoxic activity, which may lead to cell death or mutagenesis. NMOR is formed in various industrial processes, including the synthesis of certain chemicals and in the preservation of cosmetic and personal care products. This compound can be used as analytical reference material. NMOR is used as a tumor initiator. It is a reagent for preparing carcinogenic animal diseases model. NMOR has other widespread utilization in laboratory and industrial environments. NMOR exhibits potent oxidizing properties, making it valuable in various applications, including as a bulding block for synthesis, environmental monitoring, and as a reagent in laboratory settings. It serves as a vital component in the synthesis of diverse compounds and functions as an analytical reagent.
Purity:
>98% (GC)
Signal Word:
Danger
SMILES:
O=NN1CCOCC1
Solubility Chemicals:
Soluble in DMSO. Sligthly soluble in methanol.
Source / Host:
Synthetic
Transportation:
Excepted Quantity
UN Nummer:
UN2811
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) H.S. Taper, et al.; Cancer Res. 31, 913 (1971) | (2) R. Prakin, et al.; Mutat. Res. 21, 155 (1973) | (3) C.E. Kimble, et al.; Mutat. Res. 31, 153 (1975) | (4) K.D. Brunnemann, et al.; Carcinogenesis 3, 693 (1982) | (5) J.B. Morrison & S.S. Hecht; IARC Sci. Publ. 57, 185 (1984) | (6) R.G. Klein, et al.; Exp. Pathol. 40, 189 (1990) | (7) P.A. Munzel, et al.; Biochem. Pharnacol. 42, 365 (1991) | (8) S. Tudzarova-Trajkovska & J. Wesierska-Gadek; J. Cell Biochem. 90, 837 (2003) | (9) S. Robichova, et al.; Chem. Biol. Interact. 148, 163 (2004) | (10) C.M. Glover, et al.; Water Res. 148, 306 (2019) | (11) Y. Li & S.S. Hecht; Int. J. Mol. Sci. 23, 4559 (2022) | (12) M. Bignami, et al.; Efsa J. 21, e07884 (2023)