Woollins' Reagent
| Code | Size | Price |
|---|
| CDX-W0019-G001 | 1 g | £80.00 |
Quantity:
| CDX-W0019-G005 | 5 g | £289.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short term: +4°C, Long term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
2,4-Diphenyl-1,3-diselenadiphosphetane 2,4-diselenide
Appearance:
Red powder.
CAS:
122039-27-4
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS06, GHS08, GHS09
Handling Advice:
Keep under inert gas.Very hygroscopic.
Hazards:
H301 + H331 - H373 - H410
InChi:
InChI=1S/C12H10P2Se4/c15-13(11-7-3-1-4-8-11)17-14(16,18-13)12-9-5-2-6-10-12/h1-10H
InChiKey:
GKYFQRQKPYPLGJ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 122039-27-4. Formula: C12H10P2Se4. MW: BD9837. Woollins' Reagent is an organophosphorus compound that finds widespread utilization as a reagent in organic synthesis. Woollins' Reagent participates in diverse reactions, such as yielding spiro heterocycles when combined with benzoic hydrazides, generating secondary amines, forming 10-membered phosphorus-selenium heterocycles in conjunction with aromatic diols, and facilitating ring-opening deselenation and phosphorus-phosphorus coupling. Woollins' Reagent has contributed to the synthesis of biologically active compounds, including anticancer drugs, antibiotics and antiviral agents.
MDL:
MFCD21362412
Molecular Formula:
C12H10P2Se4
Molecular Weight:
532
Package Type:
Vial
PG:
III
Precautions:
P273 - P301 + P310 + P330 - P304 + P340 + P311 - P314
Product Description:
Woollins' Reagent is an organophosphorus compound that finds widespread utilization as a reagent in organic synthesis. Woollins' Reagent participates in diverse reactions, such as yielding spiro heterocycles when combined with benzoic hydrazides, generating secondary amines, forming 10-membered phosphorus-selenium heterocycles in conjunction with aromatic diols, and facilitating ring-opening deselenation and phosphorus-phosphorus coupling. Woollins' Reagent has contributed to the synthesis of biologically active compounds, including anticancer drugs, antibiotics and antiviral agents.
Purity:
>95% (NMR)
Signal Word:
Danger
SMILES:
[Se]=P([Se]1)(C2=CC=CC=C2)[Se]P1(C3=CC=CC=C3)=[Se]
Solubility Chemicals:
Soluble in DMSO or chloroform.
Source / Host:
Synthetic
Transportation:
Excepted Quantity
UN Nummer:
UN3283
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) G. Hua, et al.; Org. Lett. 8, 525 (2006) | (2) D.B. Cordes, et al.; Acta Crystallpgr. C 67, o509 (2011) | (3) G. Hua, et al.; ACS Omega 5, 11744 (2020) | (4) G. Hua & J.D. Woollins; ACS Omega 6, 31228 (2021) | (5) L.E. English, et al.; Chemistry 28, e202200376 (2022) | (6) P.N. Makhal, et al.; Chem Commun. 59, 3767 (2023)