Recombinant Human IL-1b
| Code | Size | Price |
|---|
| ELK-EPT039-10ug | 10ug | £260.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped on dry ice/polar packs.
Storage:
Store at -70°C, stable for 6 months after receipt. Store at -70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Further Information
Accession:
P01584
Alternative Names:
Interleukin-1 beta; Catabolin; IL1F2; IL1B
Apparent Molecular Weight:
17 KDa, reducing conditions
Background:
IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Biological Activity:
Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells(Cat#XCC10). The ED50 for this effect is 20-100 pg/ml.
Endotoxin:
Less than 0.001 ng/ug (0.01 EU/ug) as determined by LAL test.
Molecular Weight:
17.5 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.