Recombinant Human Galectin 9 (C-6His)
| Code | Size | Price |
|---|
| ELK-EPT189-50ug | 50ug | £460.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
The product is shipped at ambient temperature.
Storage:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Accession:
Q3B8N1-2
Alternative Names:
Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9
Apparent Molecular Weight:
49 KDa, reducing conditions
Background:
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Biological Activity:
Immobilized Human Galectin 9-His (Cat#C808) at 10ug/ml (100 ul/well) can bind Human TIM-3-His* (Cat#C356).*: Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human TIM-3-His (Cat#C356) is 8-40 ug/ml.
Endotoxin:
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Molecular Weight:
36.7 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Redissolve:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100ug/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.?