Il-17a Antibody (Antigen affinity purified)

NSJ Bioreagents
Product Code: NSJ-RQ6646
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6646-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
After reconstitution, the Il-17a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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IHC staining of FFPE rat spleen tissue with Il-17a antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.~
2 / 2
IHC staining of FFPE mouse spleen tissue with Il-17a antibody. HIER: boil tissue sections in pH8 EDTA

IHC staining of FFPE rat spleen tissue with Il-17a antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.~
IHC staining of FFPE mouse spleen tissue with Il-17a antibody. HIER: boil tissue sections in pH8 EDTA

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Il-17a antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant rat protein (amino acids A18-S150) was used as the immunogen for the Il-17a antibody.
Limitation:
This Il-17a antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q61453