PTPN2 Antibody / Protein tyrosine phosphatase non receptor type 2 (Antigen affinity purified)

NSJ Bioreagents
Product Code: NSJ-RQ6673
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6673-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the TCPTP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Flow cytometry testing of human PC-3 cells with TCPTP antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= TCPTP antibody.~
2 / 2
Western blot testing of human 1) HeLa and 2) K562 cell lysate with TCPTP a

Flow cytometry testing of human PC-3 cells with TCPTP antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= TCPTP antibody.~
Western blot testing of human 1) HeLa and 2) K562 cell lysate with TCPTP a

Documents

Further Information

Application Details:
Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the TCPTP antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
TCPTP, also called as PTPN2, is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids M1-R255) was used as the immunogen for the TCPTP antibody.
Limitation:
This TCPTP antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P17706