Aromatase Antibody / CYP19A1 (Antigen affinity purified)

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NSJ Bioreagents
Product Code: NSJ-RQ6861
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6861-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the Aromatase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) rat testis, 2) rat ovary, 3) rat brain, 4) rat C6, 5) mouse testis, 6) mouse ovary, 7) mouse brain and 8) mouse NIH 3T3 cell lysate with Aromatase antibody. Predicted molecular weight ~58 kDa.~
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Western blot testing of hu
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Western blot testing of 1) rat testis, 2) rat ovary, 3) rat brain, 4) rat C6, 5) mouse testis, 6) mouse ovary, 7) mouse brain and 8) mouse NIH 3T3 cell lysate with Aromatase antibody. Predicted molecular weight ~58 kDa.~
Western blot testing of hu

Documents

Further Information

Application Details:
Western blot: 1-2ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Aromatase antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
CYP19A1, also called Aromatase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The CYP19 gene spans at least 70 kb of genomic DNA and contains 10 exons. By in situ hybridization, the ARO gene is mapped to 15q21.1. The aromatase enzyme can be found in many tissues including gonads, brain, adipose tissue, placenta, blood vessels, skin, bone, and endometrium, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer. It is an important factor in sexual development. Some bodybuilders taking steroids also take antiaromatase supplements to prevent excess testosterone conversion into estrogens, which can cause gynecomastia.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant mouse protein (amino acids N75-Q428) was used as the immunogen for the Aromatase antibody.
Limitation:
This Aromatase antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P28649