Acid Phosphatase Antibody / ACP2 (Lysosomal) (Antigen affinity purified)

NSJ Bioreagents
Product Code: NSJ-RQ6918
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6918-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the ACP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) human T-47D, 2) human HeLa, 3) human U-251, 4) human RT4, 5) rat liver, 6) rat pancreas, 7) mouse liver and 8) mouse pancreas tissue lysate with ACP2 antibody. Predicted molecular weight ~76 kDa.

Western blot testing of 1) human T-47D, 2) human HeLa, 3) human U-251, 4) human RT4, 5) rat liver, 6) rat pancreas, 7) mouse liver and 8) mouse pancreas tissue lysate with ACP2 antibody. Predicted molecular weight ~76 kDa.

Documents

Further Information

Application Details:
Western blot: 0.5-1 ug/ml
Application Note:
Optimal dilution of the ACP2 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids RSLRFVTLLYRHGDRSPVKTYPKDPYQE were used as the immunogen for the ACP2 antibody.
Limitation:
This ACP2 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P11117