uPAR Antibody / uPA Receptor (Antigen affinity purified)

Contact us
NSJ Bioreagents
Product Code: NSJ-RQ6957
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6957-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the PLAUR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

1 / 1
Western blot testing of 1) human HeLa, 2) human Raji, 3) human COLO-320, 4) human MCF7, 5) rat brain, 6) rat thymus and 7) mouse brain lysate with PLAUR antibody. Expected molecular weight: 37-60 kDa, depending on glycosylation level.
❮❯

Western blot testing of 1) human HeLa, 2) human Raji, 3) human COLO-320, 4) human MCF7, 5) rat brain, 6) rat thymus and 7) mouse brain lysate with PLAUR antibody. Expected molecular weight: 37-60 kDa, depending on glycosylation level.

Documents

Further Information

Application Details:
Western blot: 0.5-1 ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the PLAUR antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
PLAUR (PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids E128-R167) was used as the immunogen for the PLAUR antibody.
Limitation:
This PLAUR antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q03405