UGT1A10 Antibody / UDP-glucuronosyltransferase 1A10 (Antigen affinity purified)

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NSJ Bioreagents
Product Code: NSJ-RQ7048
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7048-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the UDP-glucuronosyltransferase 1A10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Flow cytometry testing of human Daudi cells with UDP-glucuronosyltransferase 1A10 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= UDP-glucuronosyltransferase 1A10 antibody.~
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Western blot testing
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Flow cytometry testing of human Daudi cells with UDP-glucuronosyltransferase 1A10 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= UDP-glucuronosyltransferase 1A10 antibody.~
Western blot testing

Documents

Further Information

Application Details:
Western blot: 0.5-1 ug/ml,Flow cytometry: 1-3ug/million cells
Application Note:
Optimal dilution of the UDP-glucuronosyltransferase 1A10 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
UDP-glucuronosyltransferase 1-10 is an enzyme that in humans is encoded by the UGT1A10 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids HIVHLEDHLFCQYLFRNALEIASEILQ were used as the immunogen for the UDP-glucuronosyltransferase 1A10 antibody.
Limitation:
This UDP-glucuronosyltransferase 1A10 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q9HAW8