COX4I1 Antibody / COX IV-1 (Antigen affinity purified)

Western blot: 0.5-1 ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml

Optimal dilution of the COX4I1 antibody should be determined by the researcher.

Lyophilized from 1X PBS with 2% Trehalose

Cytochrome c oxidase subunit 4 isoform 1, mitochondrial is an enzyme that in humans is encoded by the COX4I1 gene. Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14.

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Amino acids EVAHVKHLSASQKALKEK were used as the immunogen for the COX4I1 antibody.

This COX4I1 antibody is available for research use only.

Cytoplasmic

Antigen affinity purified

P13073