Estrogen Receptor alpha Antibody [Clone rESR1/7162] (Purified)
| Code | Size | Price |
|---|
| NSJ-V4010-20UG | 20 ug | £264.00 |
Quantity:
| NSJ-V4010-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: rESR1/7162
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the recombinant Estrogen Receptor alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the recombinant Estrogen Receptor alpha antibody should be determined by the researcher.
Description:
Recognizes a protein of 67kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to antiestrogen (e.g. tamoxifen) therapy.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant fragment corresponding to the C-terminus from the human ER alpha was used as the immunogen for the recombinant Estrogen Receptor alpha antibody.
Limitation:
This recombinant Estrogen Receptor alpha antibody is available for research use only.
Purity:
Protein A/G affinity
Uniprot #:
P03372