c-Kit Antibody / CD117 / SCFR [Clone C117/7119] (Purified)

NSJ Bioreagents
Product Code: NSJ-V4028
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V4028-20UG20 ug£264.00
Quantity:
NSJ-V4028-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: C117/7119
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the SCFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC staining of FFPE human gastrointestinal stromal tumor (GIST) with SCFR antibody (clone C117/7119) at 2ug/ml. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

IHC staining of FFPE human gastrointestinal stromal tumor (GIST) with SCFR antibody (clone C117/7119) at 2ug/ml. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Documents

Further Information

Application Details:
ELISA: 2-4ug/ml (order Ab without BSA for coating),Immunohistochemistry (FFPE): 2-4ug/ml
Application Note:
Optimal dilution of the SCFR antibody should be determined by the researcher.
Description:
c-Kit, also called CD117, SCFR and Stem Cell Factor Receptor is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-SCFR has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-SCFR is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 50-250 from the human protein was used as the immunogen for the SCFR antibody.
Limitation:
This SCFR antibody is available for research use only.
Localization:
Cell surface, cytoplasm
Purity:
Protein A/G affinity
Uniprot #:
P10721