c-Kit Antibody / CD117 / SCFR [Clone C117/7119] (Purified)
Code | Size | Price |
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NSJ-V4028SAF-100UG | 100 ug | £534.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: C117/7119
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the SCFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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Further Information
Application Details:
ELISA: 2-4ug/ml (order Ab without BSA for coating),Immunohistochemistry (FFPE): 2-4ug/ml
Application Note:
Optimal dilution of the SCFR antibody should be determined by the researcher.
Description:
c-Kit, also called CD117, SCFR and Stem Cell Factor Receptor is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-SCFR has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-SCFR is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A portion of amino acids 50-250 from the human protein was used as the immunogen for the SCFR antibody.
Limitation:
This SCFR antibody is available for research use only.
Localization:
Cell surface, cytoplasm
Purity:
Protein A/G affinity
Uniprot #:
P10721