CD31 Antibody / PECAM-1 [Clone PECAM1/4341] (Purified)

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NSJ Bioreagents
Product Code: NSJ-V4043
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V4043-20UG20 ug£264.00
Quantity:
NSJ-V4043-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: PECAM1/4341
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the CD31 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CD31 antibody (clone PECAM1/4341). These results demonstrate the foremost specificity of the PECAM1/4341 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CD31 antibody (clone PECAM1/4341). These results demonstrate the foremost specificity of the PECAM1/4341 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the CD31 antibody should be determined by the researcher.
Description:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 1-350 from the human protein was used as the immunogen for the CD31 antibody.
Limitation:
This CD31 antibody is available for research use only.
Purity:
Protein A/G affinity
Uniprot #:
P16284