PHOX2B Antibody [Clone PHOX2B/7161R] (Purified)
| Code | Size | Price |
|---|
| NSJ-V4057SAF-100UG | 100 ug | £534.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG, kappa
Antibody Clonality: Monoclonal
Antibody Clone: PHOX2B/7161R
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the recombinant PHOX2B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the recombinant PHOX2B antibody should be determined by the researcher.
Description:
Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for the formation of autonomic ganglia in the autonomic nervous system. PHOX2B is expressed in neuroblastoma, brain and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2).
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A human PHOX2B partial protein was used as the immunogen for the recombinant PHOX2B antibody.
Limitation:
This recombinant PHOX2B antibody is available for research use only.
Localization:
Nucleus
Purity:
Protein A/G affinity
Uniprot #:
Q99453