CD1B Antibody

NSJ Bioreagents
Product Code: NSJ-RQ7066
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7066-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the CD1b antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) human HCCT, 2) human MOLT4, 3) human Jurkat, 4) rat thymus, 5) mouse thymus, 6) mouse RAW264.7 and 7) mouse ANA-1 cell lysate with CD1b antibody. The predicted molecular weight is ~37 kDa but is often observed higher due to glycosylation.

Western blot testing of 1) human HCCT, 2) human MOLT4, 3) human Jurkat, 4) rat thymus, 5) mouse thymus, 6) mouse RAW264.7 and 7) mouse ANA-1 cell lysate with CD1b antibody. The predicted molecular weight is ~37 kDa but is often observed higher due to glycosylation.

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the CD1b antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
CD1B is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids D78-Y110) was used as the immunogen for the CD1b antibody.
Limitation:
This CD1b antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P29016