Cxcr5 Antibody / Blr1 / Mdr15

NSJ Bioreagents
Product Code: NSJ-RQ7071
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7071-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
After reconstitution, the Blr1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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IHC staining of FFPE rat lymph node tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.~
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IHC staining of FFPE mouse spleen tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA f

IHC staining of FFPE rat lymph node tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.~
IHC staining of FFPE mouse spleen tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA f

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Blr1 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
CXCR5 (Chemokine CXC Motif Receptor 5), also known as BLR1 (Burkitt lymphoma receptor 1) and MDR15 (Monocyte derived receptor 15), is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemo-attractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma (PIOL).
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant mouse protein (amino acids M1-F374) was used as the immunogen for the Blr1 antibody.
Limitation:
This Blr1 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q04683