GRAF Antibody / ARHGAP26

NSJ Bioreagents
Product Code: NSJ-RQ7144
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7144-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the ARHGAP26 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) human HeLa, 2) human MCF7, 3) human RT4, 4) human U-251, 5) rat brain and 6) mouse brain tissue lysate with ARHGAP26 antibody. Predicted molecular weight ~92 kDa (isoform 1) and ~86 kDa (isoform 2).

Western blot testing of 1) human HeLa, 2) human MCF7, 3) human RT4, 4) human U-251, 5) rat brain and 6) mouse brain tissue lysate with ARHGAP26 antibody. Predicted molecular weight ~92 kDa (isoform 1) and ~86 kDa (isoform 2).

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the ARHGAP26 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids S584-E791) was used as the immunogen for the ARHGAP26 antibody.
Limitation:
This ARHGAP26 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q9UNA1