CXCR5 Antibody / BLR1 / MDR15

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NSJ Bioreagents
Product Code: NSJ-RQ7162
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7162-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the MDR15 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Flow cytometry testing of human HEL cells with MDR15 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MDR15 antibody.~
2 / 2
Western blot testing of 1) human Raji, 2) human MOLT4, 3) human HeLa, 4) rat
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Flow cytometry testing of human HEL cells with MDR15 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MDR15 antibody.~
Western blot testing of 1) human Raji, 2) human MOLT4, 3) human HeLa, 4) rat

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the MDR15 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
CXCR5 (Chemokine CXC Motif Receptor 5), also known as BLR1 (Burkitt lymphoma receptor 1) and MDR15 (Monocyte derived receptor 15), is a G protein-coupled seven transmembrane receptor for chemokine CXCL13(also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids A181-S358) was used as the immunogen for the MDR15 antibody.
Limitation:
This MDR15 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P32302