Fanca Antibody / Fanconi anemia group A protein

NSJ Bioreagents
Product Code: NSJ-RQ7171
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7171-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the Fanca antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Flow cytometry testing of mouse ANA-1 cells with Fanca antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fanca antibody.~
2 / 2
Western blot testing of 1) rat testis and 2) mouse thymus tissue lysate wit

Flow cytometry testing of mouse ANA-1 cells with Fanca antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fanca antibody.~
Western blot testing of 1) rat testis and 2) mouse thymus tissue lysate wit

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Fanca antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development; regulation of CD40 signaling pathway; and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut; liver; lung; reproductive system; and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple); acute myeloid leukemia; esophagus squamous cell carcinoma; ovarian disease (multiple); and skin melanoma. Orthologous to human FANCA (FA complementation group A).
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant mouse protein (amino acids E1272-F1439) was used as the immunogen for the Fanca antibody.
Limitation:
This Fanca antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q9JL70