FXR2 Antibody / Fragile X mental retardation syndrome-related protein 2

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NSJ Bioreagents
Product Code: NSJ-RQ7174
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7174-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Monkey
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the FXR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Flow cytometry testing of mouse HEPA1-6 cells with FXR2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= FXR2 antibody.
2 / 3
Flow cytometry testing of human RT4 cells with FXR2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= FXR2 antibody.
3 / 3
Western blot testing of 1) monkey COS-7, 2) human U-251 and 3) human SH-SY5Y cell lysate with FXR2 antibody. Predicted molecular weight ~74 kDa but commonly observed at up to ~100 kDa.
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Flow cytometry testing of mouse HEPA1-6 cells with FXR2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= FXR2 antibody.
Flow cytometry testing of human RT4 cells with FXR2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= FXR2 antibody.
Western blot testing of 1) monkey COS-7, 2) human U-251 and 3) human SH-SY5Y cell lysate with FXR2 antibody. Predicted molecular weight ~74 kDa but commonly observed at up to ~100 kDa.

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the FXR2 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids N153-K651) was used as the immunogen for the FXR2 antibody.
Limitation:
This FXR2 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P51116