TGFBR3 Antibody / TGF beta Receptor III

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NSJ Bioreagents
Product Code: NSJ-RQ7431
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7431-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the TGF beta Receptor III antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

1 / 2
Flow cytometry testing of human HeLa cells with TGF beta Receptor III antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= TGF beta Receptor III antibody.~
2 / 2
Western blot testing of human 1) A549 and 2)
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Flow cytometry testing of human HeLa cells with TGF beta Receptor III antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= TGF beta Receptor III antibody.~
Western blot testing of human 1) A549 and 2)

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the TGF beta Receptor III antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Betaglycan also known as Transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan >300 kDa in molecular weight. This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids H37-R649) was used as the immunogen for the TGF beta Receptor III antibody.
Limitation:
This TGF beta Receptor III antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q03167